site stats

P16-creert2-tdtomato mouse

Web所谓 reporter鼠 ,就是敲入了报告基因(reporter gene)的鼠。 常见的有 TdTomato鼠、mT/mG鼠、LacZ鼠、彩虹鼠 等,他们的重要作用是对各种特异性表达的Cre工具鼠进行 … WebHere, we generated a p16-Cre ERT2 -tdTomato mouse model to analyze the in vivo characteristics of p16 high cells at a single-cell level. We found tdTomato-positive p16 high cells detectable in all organs, which were enriched with age.

Ptf1a-CreERT2

WebSingle-cell RNA-seq analyses of various tissues from early middle-aged p16-CreERT2-tdTomato mice reveal that p16high cells exhibit heterogenous senescence-associated … WebThe new Gcg CreERT2 mouse line was crossed to the Rosa26 tdTomato (R26 tdTomato) Cre reporter mouse line in order to evaluate the tissue specificity, efficiency and … prince george\u0027s county population 2022 https://philqmusic.com

The RBPMS CreERT2-TdTomato Mouse for Study Retinal and …

WebFig1. CreERT2-mediated recombination in kidney of Slc34a1 CreERT2/+; Rosa26 tdTomato/+ mouse.. Fig2. CreERT2-mediated recombination in kidney of Slc34a1 CreERT2/+; Rosa26 tdTomato/+ mouse.. Fig3. Detection of tdTomato(red) in various tissues of Slc34a1 CreERT2/+; Rosa26 tdTomato/+ mice. (For more detailed information please … WebSep 19, 2024 · 図1.p16-CreERT2-tdTomatoマウスの仕組み タモキシフェン(TAM)を投与されることで、p16陽性細胞でCreERT2が核内に移行することが可能となる。 その結 … WebNational Center for Biotechnology Information prince george\u0027s county property assessment

New Tool: Microglia-Specific Reporter Mice, With Choice of Colors

Category:世界初、体内に存在する老化の原因となる細胞の解析に …

Tags:P16-creert2-tdtomato mouse

P16-creert2-tdtomato mouse

The world

WebTdTomato大鼠(SD- Gt (ROSA26)tm1 (CAG-LSL-Tdtomato) /Bcgen)在ROSA位点敲入了一个CAG启动子、TdTomato蛋白编码序列和WPRE序列,并在CAG启动子和TdTomato序列之间插入了LSL(loxp-3×stop-loxp)序列。 如图1所示。 图1. TdTomato的打靶策略 [1] 这种鼠在正常情况下由于3×stop的存在并不能表达红色荧光,当与Cre鼠或TAM激活的CreERT2鼠 … WebNov 17, 2024 · Nakanishi’s group generated a p16-CreERT2-tdTomato model, which can help analyze the dynamic properties of p16Ink4a -high cells at single-cell level, and demonstrated that elimination of...

P16-creert2-tdtomato mouse

Did you know?

WebApr 7, 2015 · Finally, the Prox1-Cre-tdTomato mouse allowed to directly visualize and monitor over time by IVM the first morphological changes of LVs that occur during acute … WebLanguage: English . 中文; 日本語; 한국어; Settings; Exit; Sign in; Products . U-GEMMs . Toolbox of Mice

WebSep 22, 2024 · Here, we generated a p16-CreERT2-tdTomato mouse model to analyze the in vivo characteristics of p16high cells at a single-cell level. We found tdTomato-positive … WebThe RBPMS CreERT2-TdTomato Mouse for Study Retinal and Vascular Relevant Disease. Number of pages: 42 Posted: 13 Apr 2024. Ying-Feng Zheng, Guilan Li, Yuanting Luo, Qikai Zhang, Yizhi Liu and Sneak Peek Administrator.

WebSep 20, 2024 · Here, we generated a p16-Cre ERT2-tdTomato mouse model to analyze the in vivo characteristics of p16 high cells at a single-cell level. We found tdTomato-positive … WebFigure Legend Snippet: ( A ) Representative images of single-cell traced tdTomato + CSF-cNs (white) at the cervical level of Rosa26 lsl - tdTomato mice injected with a low dose of adeno-associated virus-Syn-Cre. 4′,6-diamidino-2-phenylindole (DAPI), blue. Projections of four CSF-cNs were traced by IMARIS software (indicated in different colors) and are …

WebValidation of MEFs from p16-CreERT2-tdTomato Mice In Vitro (A) Scheme of p16-CreERT2-tdTomato mice. (B) Proportion of Tom+ in young (Passage 2) and replicative senescent MEFs (Passage 8) treated with 4-OHT for 3 days. (C) Immunostaining of MEFs treated as in (B) using the indicated antibodies. Scale bar, 10 μm.

WebTo better understand the roles of p16 in pancreatic tumorigenesis, we created a conditional p16 knockout mouse line (p16flox/flox), in which p16 is specifically disrupted in a tissue … please anythingWebSep 11, 2024 · Here, we generated a p16-CreERT2-tdTomato mouse model to analyze the in vivo characteristics of p16high cells at a single-cell level. We found tdTomato-positive … prince george\u0027s county property linesWebOct 12, 2024 · 东京大学医学科学研究所中西诚诚教授领导的研究小组生成了p16-Cre ERT2-tdTomato小鼠模型,以在单细胞水平上表征体内p16高细胞。 他们发现在所有器官中都 … please any key ゲームWebResults: Tamoxifen induction at the three different time points resulted in PC-specific expression of tdTomato in both reporter models. In the NG2-CreER™-tdTomato mouse, the induction efficiency ranged from 21.9 to 35.5%. In the PDGFRb-P2A-CreER T2 -tdTomato mouse, an induction efficiency between 78.9 and 94.1% was achieved. please any key to shutdownWebThe research team generate a p16-Cre ERT2 - tdTomato mouse model to uncover the in vivo dynamics and properties of p16high cells. Single-cell RNA- prince george\u0027s county procurement bidsWebApr 13, 2024 · Here, we develop one tamoxifen inducible RBPMS-tdTomato reporter mouse line, which allowed the precise identification and tracking of the RBPMS expressing cells … prince george\u0027s county property line mapprince george\u0027s county property owner search