WebSLC11A1 (formerly Human natural resistance–associated macrophage protein 1 (NRAMP1)) has been associated with susceptibility to tuberculosis. 94 The importance of SLC11A1 in animal models of granulomatous disorders and its putative role in macrophage activation make it an attractive candidate gene in SA. WebThe LST1 gene is located in the MHC class III cluster between the MHC class I and II regions. While most genes in this cluster have been sufficiently characterised, a definitive function and expression pattern for LST1 still remains elusive.
SLC11A1 - an overview ScienceDirect Topics
WebApr 30, 2011 · Here we investigate SLC11A1 and VL in India. Methods Nine polymorphisms (rs34448891, rs7573065, rs2276631, rs3731865, rs17221959, rs2279015, rs17235409, rs17235416, rs17229009) that tag linkage disequilibrium blocks across SLC11A1 were genotyped in primary family-based (313 cases; 176 families) and replication (941 cases; … WebApr 27, 2011 · SLC11A1 is expressed in monocytes [10,11], which are the circulating precursors of macrophages and DCs, the major antigen-presenting cells in the immune system. SLC11A1 has pleiotropic effects on macrophage function, all of which are important in resistance to intracellular pathogens. black screen on edge
No evidence for association between SLC11A1 and visceral …
WebSingle cell type specificityi. The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more. Webthe genetic association of SLC11A1 polymorphisms with susceptibility to leishmaniasis. Genotypes and other risk-related data werecollectedfrom13case-controlandfamily-basedstudies(afterliteraturesearch).Conventionalrandom-effectsmeta-analysis was performed using STATA 13. WebMay 20, 2011 · SLC11A1 has pleiotropic effects on macrophage function and remains a strong candidate for infectious disease susceptibility. 5' and/or 3' polymorphisms have been associated with tuberculosis, leprosy, and visceral leishmaniasis (VL). Most studies undertaken to date were under-powered, and none has been replicated within a population. garrett temple wife