Tfrc knockin
Web9 Apr 2024 · Summary. This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for … Web17 Jan 2024 · Transferrin receptor (TFRC), which was overexpressed in cervical cancer and involved in the HIF-1 pathway, was associated with advanced clinical pathologic …
Tfrc knockin
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WebTFRC CRISPR Knock Out Line. Technique. CV40 transformed cell line or 293tsA1609neo from human kidney 293 cells delivered as 1. Species. Human, Humans. Alternative name. … WebTFRC INFORMATION. Proteini. Full gene name according to HGNC. Transferrin receptor. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. TFRC (CD71, p90, TFR1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
Web2 May 2024 · The TfR-mediated incorporation of JR-141 was confirmed by using human fibroblasts in vitro. When administrated intravenously to hTfR knockin mice or monkeys, … Web17 Jan 2024 · Transferrin receptor (TFRC), which was overexpressed in cervical cancer and involved in the HIF-1 pathway, was associated with advanced clinical pathologic characteristics. It was also an...
Web5 Nov 2024 · The IREB2 gene encodes an iron-responsive element-binding protein (IRP) that regulates the expression of proteins involved in iron metabolism by binding to iron-responsive elements in the mRNAs of target genes, which include the transferrin receptor (TFRC; 190010) as well as the heavy and light ferritin chains (FTH1, 134770 and FTL, … WebTransferrin Receptor Protein-1 (TFRC) is a cell surface receptor that binds ferric-iron-loaded transferrin in the bloodstream at high affinity to facilitate iron uptake into cells. TFRC is …
WebFig. 1. The central biochemical event of ferroptotic cancer cell death. The central biochemical event of ferroptosis is involved in iron accumulation and lipid peroxidation, which leads to oxidative injury and cell death. ROS, reactive oxygen species. Iron is an important trace element in many species.
Web28 Mar 2024 · This is the website of the Time For Real Change in UNISON campaign. UNISON is crying out for real change. We are rank and file UNISON activists determined to make our union democratic, transparent and successful - a fighting union that delivers for its members. Find out more about us and get involved with our campaign on our website. pec bcc san micheleWeb5 Jul 2024 · The Tfrc AKO mice were also protected from obesity induced by a high-fat diet (HFD). Compared with control mice, Tfrc AKO mice had increased iron storage in the liver and a lower adipose mass ... meaning of gleason scoresWebTransferrin receptor 1. Transferrin receptor protein 1 ( TfR1 ), also known as C luster of D ifferentiation 71 ( CD71 ), is a protein that in humans is encoded by the TFRC gene. [5] [6] … pec board feelingsWeb24 Jan 2024 · Transferrin receptor 1 (Tfr1) mediates uptake of circulating transferrin-bound iron to developing erythroid cells and other cell types. Its critical physiological function is highlighted by the embryonic lethal phenotype of Tfr1-knockout (Tfrc -/-) mice and the pathologies of several tissue-specific knockouts. meaning of glentWebTFRC Knockout Cell Line-HeLa Cat.No. CSC-RT1891 Description HeLa -TFRC (-/-) is a stable cell line with a homozygous knockout of human TFRC using CRISPR/Cas9. Host Cell HeLa Shipping 1 vial of knockout cell line and 1 vial of wildtype cell line Storage Liquid nitrogen Gene Information Gene Name TFRC Gene Symbol TFRC Gene ID 7037 Q&A meaning of gledemeaning of glendaWeb16 Apr 2024 · The TFRC-sh, TFRC-OE, SLC7A11-sh, and SLC7A11-OE plasmids were purchased from GeneChem (Shanghai, China). The plasmids with truncated TFRC promoter regions that were cloned into pGL3 were ... pec blocks